Postgraduate Seminar Presentation : Copper-containing transparent coatings with long-term antibacterial efficacy

Speaker Debirupa Mitra (Supervisor: Prof Neoh Koon Gee)

Host

Date/Time 16 Nov - 16 Nov, 2.00PM

Venue E5-02-32 , Faculty of Engineering, National University of Singapore

Synopsis

Bacteria-contaminated inanimate surfaces within hospitals/clinics result in transmission of pathogens via direct or indirect contact, leading to increased risk of healthcare-associated infections (HAIs). The use of antibacterial coatings is a potential way of reducing transmission of bacteria. In this work, surface modification of transparent polyvinyl fluoride (PVF) films with covalently grafted positively charged polymer (chitosan derivative) resulted in 90% reduction in viable bacteria. In an effort to increase the efficacy, copper was incorporated on to the polymer modified PVF via two different strategies. The copper-containing coatings were transparent and resulted in 100% reduction in viable bacteria, while being non-cytotoxic to mammalian cells. Additionally, these coatings are transparent and possess long-term antibacterial efficacy for potential application in clinical environment.

Biography