Issue 3 (2016)

  • In silico screening of metal-organic frameworks for CO2 separation

    By sophisticated molecular simulations, 4764 computation-ready, experimental metal-organic frameworks (CoRE-MOFs) have been screened for CO2 separation from flue gas (CO2/N2) and natural gas (CO2/CH4). Quantitative relationships are established, for the first time, between metal type and adsorbent evaluation criteria (adsorption selectivity and capacity, working capacity and regenerability)....

    Jianwen JIANG

  • Tuning Endothelial Permeability with Functionalized Nanodiamonds

    Cancer nanomedicine vehicles are required to cross the vascular barrier to reach the tumor site in order to ensure the successful delivery of their therapeutic load. Here, nanodiamond (ND) variants were shown to induce surface dependent vascular barrier leakiness. The ND-induced leakiness was found to be mediated by the increase in intracellular reactive oxygen species (ROS) and Ca2+ . These...

    David Tai Wei LEONG

  • Rapid methane hydrate formation to develop a cost effective large scale energy storage system

    SNG (solidified natural gas) technology is a cost effective and environmentally benign option to store natural gas at a large scale and in a safe manner. In this study, we report a simple method to produce methane hydrates rapidly for the first time employing an unstirred reactor configuration in presence of tetrahydrofuran (THF) as a promoter. We report about 70% of water conversion to...

    Praveen LINGA

  • Waste Shells to Chemicals and Materials

    Singapore is reputed for tasty seafood such as chili crab. 60% of a crab’s weight, belonging to the shell, is typically left as waste. About 1.5 million tons of such waste is generated annually in Southeast Asia region, most of which is dumped or landfilled without utilization. We proposed a new concept, entitled “waste-shell-refinery”, to transform “waste” into “wealth”. By analogy with...

    Ning YAN

  • Design of DNA Monomers as an Amplification Toolbox

    The ability to amplify signals from biomolecular recognition events is highly sought after, particularly for detecting low target count. Hybridization chain reaction (HCR) is an attractive enzyme-free method based on the programmed self-assembly of solely DNA hairpin monomers upon activation by a complementary trigger. In this work, we established an explicit set of four-point design guidelines...

    Lanry Lin-Yue, YUNG

  • A General Synthetic Approach for Integrated Nanocatalysts

    Integration of different nanocomponents into a greater assemblage or object for applications poses a significant challenge to nanotechnology. At present, it still remains extremely difficult to achieve high monodispersivity for such assembled products. To gain better synthetic controllability, ideally, an integration of this type should be done in a stepwise manner. In this project, we...

    Hua Chun ZENG